direia Stem Intense Lotion EX Some

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Direia Stem Intense Lotion iP Some – 150 ml

Direia Stem Intense Lotion iP Some is not just a toner—it’s a regenerative elixir. Drawing on the latest in stem cell science, it combines Stem Bio Complex, iPS cell supernatant, and mesenchymal cell exosomes to awaken your skin’s natural repair system. This “3-Step” approach (Regenerate → Innovate → Reboot) helps boost firmness, improve texture, and support long-term cellular health. The formula is reinforced with antioxidants and energy-boosting molecules for skin that looks and feels revitalized.

Key Benefits:

  • Stimulates skin cell regeneration using iPS cell supernatant & human stem cell culture fluid.  
  • Delivers deep hydration to improve elasticity and barrier strength.  
  • Reboots skin’s vitality and functional capacity with long-lasting active delivery.  
  • Brightens and protects with antioxidant support from glutathione and vitamin C derivatives.  
  • Lightweight yet rich texture that fits into both morning and evening routines.  

Key Ingredients:

  • iPS Cell Conditioned Supernatant: Delivers powerful growth factors derived from induced pluripotent stem cells to signal renewal deep in the dermis.  
  • Mesenchymal Cell Exosomes: Act as biological messengers, directing stem cell and peptide activity precisely where needed.  
  • Vitamin C Derivative (Ascorbic Acid & Peptide): A multi-functional antioxidant that helps brighten and protect.  
  • NMN Derivative / Dihydronicotinamide Riboside: Supports skin energy metabolism and anti-aging functions.  
  • Botanical Extracts (Plantago major seed, Epilobium fleischeri, Geranium): Soothe, reinforce, and balance the skin’s surface.  

How to Use:

  1. After cleansing, dispense approximately the size of a 500-yen coin (about a palmful) into a cotton pad or directly into your clean hands.  
  2. Gently sweep or pat across your face and neck, allowing the lotion to absorb completely.
  3. Use morning and evening. One 150 ml bottle lasts approximately 1.5 months with twice-daily use.  

Sustainability / Ethical Commitments:

  • Manufactured in Japan by Grazia with strict quality control.  
  • Formulated without harsh, unnecessary additives. (No excessive alcohol, fragrance, or mineral oil in typical water-based lotions.)   

Certifications / Clinical Relevance:

  • Uses a Stem Bio Complex combining stem cell media and exosomes, informed by regenerative medicine research.  
  • Enhanced delivery via 3D Nanotechnology (gel matrix slowly releases actives for sustained effect). 

FAQ:

・Is this lotion safe for all skin types, including sensitive skin?

Yes, the formula is designed for regenerative support and is relatively gentle. Still, a patch test is recommended for highly sensitive users. 

・Can I use this with other active serums or anti-aging products?

Yes. Because this lotion supports deep regeneration, it plays well with serums, peptides, and retinoids. Apply the lotion first before other treatments.

・What makes this different from a regular hydrating lotion?

Unlike basic hydrating toners, this is a regenerative lotion: it uses iPS-cell media, exosomes, and stem-cell-derived growth factors to actually support skin renewal and longevity. 

・Will it make my skin sticky or greasy?

No — it has a rich but refined texture that absorbs well without leaving greasiness. Use the recommended amount for best feel.

We ship internationally from our warehouse here in Tokyo. We use the services of third-party delivery service providers, namely, Japan Post (EMS) and Airmail, for shipping all the orders placed by our customers. View our entire policy here.

Every skin is different, therefore, no returns are accepted simply on the account that the product had an adverse reaction on your skin, or did not provide you any particular kind of results that you were expecting. However, you may initiate a return for the defective and damaged products purchased from the website within a period of7 (seven) days calculated from the order delivery date (“Return Period”). View our entire policy here.

Water, Butylene Glycol, Glycerin, Pentylene Glycol, Conditioned Media of Immortalized Human Dental Pulp Stem Cells, Conditioned Media of Human Hepatocyte–Induced Pluripotent Stem Cells, Human Stem Cell Conditioned Media, Human Adipose-Derived Mesenchymal Stem Cell Exosomes, Standardized Cell Culture Medium 9, Ascorbic Acid, Ascorbyl Methylcarbonyl Pentapeptide-72 tri-t-Butyltryptophan Amide, Dihydronicotinamide Riboside Acetyl tri-t-Butyltryptophan, Epilobium Fleischeri Leaf/Stem Extract, Plantago Major Seed Extract, Pelargonium Graveolens Oil, Xanthan Gum, Citric Acid, Sodium Citrate, Tri(caprylic/capric) Glyceride, Hydrogenated Lecithin, Polysorbate 80, Caprylyl Glycol, Glutathione, Stearic Acid, Geranium Robertianum Extract, Laureth-4, Tocopheryl Acetate, PEG-60 Hydrogenated Castor Oil, Palmitoyl Dipeptide-18, 1,2-Hexanediol, Phenoxyethanol

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In Japan, expiration dates are usually not printed on cosmetics unless required (e.g., food or medicated products). However, we keep small stocks and order directly from manufacturers to ensure you get the freshest products. Most items have a shelf life of 2–3 years when stored properly in a cool, dry place away from direct sunlight.

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